It was once thought that Multiple Sclerosis began in the inner brain and traveled outward to the cortex, or outer layer, but researchers in Minnesota have found that the disease may actually work the other way around, going inward. This new finding may lead to unlocking the mystery that is finding a cure for M.S. This will also lead to better therapeutic options which at times, ignore the cortex. They also support that the disease is of inflammation rather than neurodegeneration.
Read about the actual research here: